ABSTRACT
The dockless e-scooter sharing service is rapidly spreading, replacing existing transportation, and improving last-mile accessibility. User segmentation with travel regularity and segment-level behavior analysis, which are already conducted in public transit, also benefits e-scooter sharing service to enhance service quality and increase usage. In this work, we group e-scooter users according to their travel regularity and identify each group's usage characteristics. Through the dockless e-scooter usage data, as operated in six cities in South Korea, travel regularity measured by users' repetitive departure time and destination is discovered and spatiotemporal usage patterns are identified. We divide e-scooter users into three groups by type of travel regularity: irregular user, spatially regular user, and regular user. Regular users more frequently use e-scooters, travel shorter distances, and walk longer distances to find an e-scooter than other groups. It is also revealed that the use in morning peak hours only occurs in the regular user group. By decomposing the temporal patterns of spatially regular and regular users, we discover that spatially regular users are composed of daytime, evening peak, and nighttime users. In contrast, regular users are composed of morning peak, evening peak, and lockdown (restriction in response to COVID-19 pandemic) peak users. This research suggests user segmentation based on travel regularity in e-scooter sharing services, enabling multiple strategies to be drawn to retain users with high regularity and convert users with low regularity to regular users.
ABSTRACT
In: Park SY, van Doren TP, Frederick J, Butler SA, Chen ZJ, Carroll L. Deconstructing "Normal” for a More Equitable Post–COVID-19 World. American Journal of Public Health 2022;112(4):533-533. https://doi.org/10.2105/AJPH.2022. 306743 Two author degrees were incorrect in the online version of the article. Lorne Carroll's degree was missing and Zhangying Jennie Chen's degree was incorrectly listed as BSN. The byline should read: Susanna Y Park, MA, Taylor P. van Doren, MA, Jynx Frederick, BSPH, Sabrina Azemar Butler, MS, Zhangying Jennie Chen, BS, and Lorne Carroll, BSN This change does not affect the paper's conclusions. https://doi.org/10.2105/AJPH.2022.306743e © 2022 American Public Health Association Inc.. All rights reserved.
ABSTRACT
Background & Aim: This study aims to examine the perception of artificial intelligence interviews experienced by prospective nursing graduates who have experienced artificial intelligence interviews at medical institutions using focus groups and provide necessary data to increase the efficiency of artificial intelligence interviews. Methods & Materials: This study was conducted to examine nursing students' artificial intelligence interview experience during COVID-19 by performing a focus group interview and qualitative content analysis. The focus group interview was carried out on November 17, 2021, to understand nursing students' artificial intelligence interview experience during COV1D-19, selecting a total of 14 senior nursing students. Results: As a result of analyzing the artificial intelligence interview experiences of nursing students who participated in this study, 35 codes, grouped into eight subcategories, were derived. They are also classified into three categories 1) Finding your way in the dark, 2) Confronting artificial intelligence, and 3) Going beyond artificial intelligence. The eight subcategories derived are as follows: 1) Vagueness, 2) Find your way, 3) The fight between artificial intelligence and me, 4) Strong questions about interview evaluation, 5) New experience, 6) Learn your own tricks for artificial intelligence interviews, 7) Setting up the environment for artificial intelligence interview, 8) Establishment of information system for artificial intelligence interview. Conclusion: Based on the results of this study, an educational program should be developed based on the main data obtained from the artificial intelligence interview experience so that nursing college students can adapt to the artificial intelligence interview.
ABSTRACT
The coronavirus disease 2019 (COVID-19) pandemic, which began in 2019, has far-reaching ramifications, including economic losses and health challenges that still affect various parts of the world. During our review, we learned that the entire world is working to stop the spread of the SARS-CoV-2 outbreak. We explore ways that may lower the danger of SARS-CoV-2 contamination and useful strategies to avoid the possibility of SARS-CoV-2 spreading through food. While hygienic protocols are required in the food supply sector, cleaning, disinfection, and the avoidance of cross-contamination across food categories and other related goods at different stages of the manufacturing process remain especially important because the virus can survive for long periods of time on inert materials such as food packaging. Furthermore, personal hygiene (regular washing and disinfection), wearing gloves and using masks, garments, and footwear dedicated to maintaining hygiene provide on-site safety for food sector personnel, supply chain intermediaries, and consumers. Restrictions imposed in response to the pandemic (e.g., closure of physical workplaces, canteens, cafes, restaurants, schools, and childcare institutions), changes in household grocery shopping frequency, individuals' perceived risk of COVID-19, income losses due to the pandemic, and sociodemographic factors are among the factors. The conclusions drawn from this study consider the implications of healthy diets, food system resilience, behavior change, and nutritional imbalance for policymakers and food supply chain participants, as well as the antimicrobial effects of vitamins and nutrients. During a public health crisis, people should eat less, necessitating preventive policies and nutritional advice to deal with this.
ABSTRACT
PurposeThis exploratory study uses a punctuated equilibrium paradigm (PEP) framework to examine the impact and adaptation of an entrepreneurial ecosystem (EE) to the COVID-19 pandemic at the organizational and ecosystem level. The aim is to provide guidance to EEs on ways to adapt to future external shocks.Design/methodology/approachAs this study is exploratory in nature, the authors use a sequential mixed method whereby a qualitative method is used first to identify emergent themes from in-depth interviews with EE members, followed by a quantitative method (survey) based on those themes across a broader cross section of EE members.FindingsEntrepreneurial ecosystem's geographical advantages have declined during the pandemic as EE firms adapted to this external shock by developing more digitally distributed organizations.Research limitations/implicationsBased on the findings, the authors propose an emerging model of EEs that extends the traditional clustering model focused on geography to account for more digitally distributed entrepreneurial clusters. However, the results, based on an in-depth study of one ecosystem, may not be fully generalizable to all EEs.Practical implicationsGiven the widespread pandemic impact, the findings may be instructive to EEs and organizations in EEs that aim to become more resilient in the face of potential future external shocks.Social implicationsAs part of the qualitative interview process the interviewees were asked what they would change in San Francisco Bay Area if they had a magic wand right now. They discussed a variety of inspiring ideas, but the most frequently mentioned was their wish to change the focus of business to solve societal problems with a global citizen mindset (e.g. recycling energy, climate change, income inequality, access to education and funding, inequity, wealth gaps, housing crisis and homelessness) to make the world a better place. Additionally, the pandemic exposed some inequality in work conditions across demographics. As firms reorganize to increase resiliency, attention to these issues should be addressed.Originality/valueThis study is unique in applying the PEP to EEs to deepen our understanding about how an EE evolves during periods of sudden external shocks.
ABSTRACT
Taste is one of the fundamental senses that allow us to distinguish nutritious food substances from toxic ones. However, the ability to taste decreases with age or can be lost due to some diseases such as COVID- 19, drugs, and disturbances in the molecular activities in taste homeostasis and renewal. Previous studies have shown the potential role of the Hedgehog signaling pathway in taste papillae homeostasis Therefore, inhibition or stimulation of the Hedgehog pathway can be explored to address taste disturbances. This study investigated photobiomodulation effects on the Hedgehog signaling pathway after inhibition with Vismodegib of taste receptor and geniculate ganglion neuronal cells in vitro and in vivo. Laser treatment performed at 630 and 850 nm, with varying energies of 30, 60, and 120J resulted in the modulation of Hedgehog signaling proteins and genes. Photobiomodulation offers a noninvasive approach with deep penetration in tissue to restore taste by promoting tastebud regeneration and stimulating desensitized afferent nerves.
ABSTRACT
Coronavirus disease 2019 (COVID-19) in patients with underlying diseases, is associated with high infection and mortality rates, which may result in acute respiratory distress syndrome and death. Mucopolysaccharidosis (MPS) type II is a progressive metabolic disorder that stems from cellular accumulation of the glycosaminoglycans, heparan, and dermatan sulfate. Upper and lower airway obstruction and restrictive pulmonary diseases are common complaints of patients with MPS, and respiratory infections of bacterial or viral origin could result in fatal outcomes. We report a case of COVID-19 in a 16-year-old adolescent with MPS type II, who had been treated with idursulfase since 5 years of age. Prior to infection, the patient’s clinical history included developmental delays, abdominal distension, snoring, and facial dysmorphism. His primary complaints at the time of admission included rhinorrhea, cough, and sputum without fever or increased oxygen demand. His heart rate, respiratory rate, and oxygen saturation were within the normal biological reference intervals, and chest radiography revealed no signs of pneumonia. Consequently, supportive therapy and quarantine were recommended. The patient experienced an uneventful course of COVID-19 despite underlying MPS type II, which may be the result of an unfavorable host cell environment and changes in expression patterns of proteins involved in interactions with viral proteins. Moreover, elevated serum heparan sulfate in patients with MPS may compete with cell surface heparan sulfate, which is essential for successful interaction between the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein and the host cell surface, thereby protecting against intracellular penetration by SARS-CoV-2.
ABSTRACT
Background: SARS-CoV-2 (i.e., COVID-19) has brought extracorporeal membrane oxygenation (ECMO) into the forefront of critical care. Its unique pathophysiology has added a level of complexity to ECMO therapy, particularly, the hematologic manifestations. Here we detail the spectrum and outcomes of bleeding complications in ECMO for COVID-19 and identify potential contributing factors. Methods: All patients who received ECMO for SARS-CoV-2 pneumonia severe acute respiratory distress syndrome at our institution between March 1, 2020 and April 12, 2021 were reviewed. Patient characteristics, laboratory results, and overall outcomes were recorded. Bleeding events were reviewed with regard to the type/location and intervention required. Severity was graded according to the degree of intervention for treatment (1 [conservative or minor] - 3 [major, life-threatening, or operative]). Laboratory results and patient characteristics were compared between patients with bleeding events and those without to identify factors associated with bleeding risk. Results: Fifty-four patients (mean age 53.2 years, 61.1% female, 51.9% Caucasian) underwent ECMO cannulation for SARSCoV-2 pneumonia at our institution. Thirty-eight (70.4%) received veno-pulmonary artery ECMO. The mean duration of support was 33.2 days with an in-hospital mortality of 42.6%. 68.5% of patients experienced at least one bleeding event during their ECMO course with 92 bleeding events (n=23 [grade 1], n=31 [grade 2], n=38 [grade 3]) over 1804 cannulation days. The most common types of bleeding types were nasal/oropharyngeal (n=30, 32.6%), pulmonary (n=18, 19.6%), and gastrointestinal (n=11, 12.0%). Eight (16.0%) patients required operative intervention and 11 (20.3%) died as a result of a bleeding event, mainly due to intracranial hemorrhages (n=5, 9.3%). There was no difference in the mean cumulative function for bleeding events between different ECMO support modalities (p=0.85) which demonstrated a linear pattern over time. Factors that increased the risk of bleeding included patient cumulative volume balance (OR 1.22 per 1000 mL increase from admission, p<0.001) while higher platelet count (OR 0.83 per 50x103/uL increase, p=0.03) was protective. Conclusion: ECMO for SARS-CoV-2 pneumonia is associated with a diverse and unique profile of bleeding complications. The incidence of bleeding complications is linearly related to cannulation duration. Certain patient factors may affect the risk of bleeding while on ECMO.
ABSTRACT
Through collaborative playlists (CPs), streaming platform users have co-curated music together for various purposes for over a decade. As the COVID-19 pandemic has transformed how people come together through technology and engage with music, CPs have also taken on new roles and value. To understand how CP usage and perception have evolved since the onset of COVID-19, we conducted a mixed-methods investigation of CPs in the United States. Survey results from primarily CP users (N=142) revealed that interest in and usage of CPs have mostly increased since the pandemic, and that the role of music in connecting with others is positively correlated with the perceived impact of COVID-19. Follow-up interviews (N=9) provided additional insights into changing perceptions and usage patterns of CPs during COVID-19;for instance, fewer collaborators per playlist reflects users' greater focus on strengthening social connections and relationships. Taken together, findings and design implications on digitally mediated co-curation further elucidate the necessity for social and collaborative experiences with music supported by CPs during COVID-19. © 2022 ACM.
ABSTRACT
Recently, chatbots have been deployed in health care in various ways such as providing educational information, and monitoring and triaging symptoms. However, they can be ineffective when they are designed without a careful consideration of the cultural context of the users, especially for marginalized groups. Chatbots designed without cultural understanding may result in loss of trust and disengagement of the user. In this paper, through an interview study, we attempt to understand how chatbots can be better designed for Black American communities within the context of COVID-19. Along with the interviews, we performed design activities with 18 Black Americans that allowed them to envision and design their own chatbot to address their needs and challenges during the pandemic. We report our findings on our participants' needs for chatbots' roles and features, and their challenges in using chatbots. We then present design implications for future chatbot design for the Black American population. © 2022 Owner/Author.
ABSTRACT
COVID-19 has been known to have a disproportionate impact on African Americans in the United States. Although studies have been conducted on the reasons for this disparity, there has been less focus on how the African American population sought trustworthy health information using technology. This is important because African Americans' mistrust of the medical system has been suggested as a possible reason for the disproportionate impact. Therefore, we conducted interviews with 18 African Americans with chronic conditions to discover what types of challenges they faced while searching for trustworthy information on COVID-19 and the strategies they used to overcome these challenges. We found that participants actively evaluated the credibility of different information sources, searched for first-hand information from people they could relate to, and tried to avoid or reduce media consumption to prevent information overload. © 2022 ACM.
ABSTRACT
African Americans have faced health disparities in terms of access to health care and treatment of illnesses. The novel coronavirus disease 2019 pandemic exacerbates those disparities caused by limited access to medical care and healthy lifestyles, vulnerability to misleading information, and mistrust of the medical profession, all of which disproportionately affect the African American population in terms of infection and mortality. Conversational agents (CAs) are a technological intervention with the potential to narrow the disparities because they make health care more accessible, are effective in disseminating health information among a population with low health literacy, and can increase users' trust in health information. However, designing CAs for this population presents challenges with regard to embodying the African American culture into CAs and addressing privacy and security concerns. This commentary discusses some advantages and challenges of using CAs to help African Americans protect themselves against coronavirus disease 2019, and calls for more research in this area. © 2020 ACM.
ABSTRACT
Background: This study aimed to investigate psychological distress among infectious disease (ID) physicians during the coronavirus disease (COVID-19) outbreak in the Republic of Korea. Methods: Using an online-based survey link sent via text message and email, we conducted a survey from April 21 to 25, 2020, targeting all ID physicians currently working in ID (n = 265). The questionnaire was based on the Maslach Burnout Inventory-Human Services Survey and the Depression, Anxiety, and Stress Scales, and information was collected on factors protecting against psychological distress and difficulties in relation to COVID-19. Results: Of 265 ID physicians, 115 (43.3%) responded, showing burnout (97, 90.4%), depression (20, 17.4%), anxiety (23, 20.0%), and stress (5, 4.3%). There were no differences in terms of distress between ID physicians who were directly involved in the care of patients with COVID-19 or not (Table 1). Greater than 50% of physicians valued their work and felt recognized by others, whereas < 10% indicated that sufficient human and financial support and private time had been provided during the outbreak. The most challenging issues concerned a lack of human resources for COVID-19 treatment or infection control, a shortage of personal protective equipment or airborne infection isolation rooms, pressure for research, and lack of guidelines for COVID-19 management (Figure 1). Conclusion: During the COVID-19 outbreak in the ROK, most respondents reported psychological distress. Preparing strategies for infectious disease outbreaks that support ID physicians is essential. (Figure Presented).
ABSTRACT
Purpose: Coronavirus Disease 2019 (COVID-19), an emerging infectious disease introduced in South Korea in 2020. Medically inclined college students are more susceptible to be infected by the virus. The purpose of this study was to investigate factors influencing preventive behavior against COVID-19 among medically inclined college students. Methods: This is a cross-sectional study using a questionnaire survey. Data were collected from 400 medically inclined college students from four colleges of medice. Independent t-test, one-way ANOVA, Pearson correlation coefficients and multiple regression analysis were conducted to analysis the data. Results: The study subjects had high knowledge and optimism related to COVID-19. Preventive behavior against COVID-19 was affected mostly by attitude (β=.32, p<.001). Such behavior was also high in relation to knowledge (β=.17, p<.001), and nursing students (β=.15, p=.002). Conclusion: Infection prevention education for medically inclined college students mainly focuses on knowledge transfer. Infection preventive education programs aimed at improving COVID-19 optimistic attitudes and knowledge are helpful for these students to maintain appropriate preventive practices. The confirmation of the importance of optimistic attitudes and risk perception toward infectious diseases through this study can provide insight into infection prevention education programs to improve practice to wards new epidemic prevention behaviors. © 2020 Korean Academy of Fundamentals of Nursing.
ABSTRACT
Background: From May to July 2015, the Republic of Korea experienced the largest outbreak of Middle East respiratory syndrome (MERS) outside the Arabian Peninsula. A total of 186 patients, including 36 deaths, had been diagnosed with MERS-coronavirus (MERS-CoV) infection as of September 30th, 2015. Materials and Methods: We obtained information of patients who were confirmed to have MERS-CoV infection. MERS-CoV infection was diagnosed using real-time reverse-transcriptase polymerase chain reaction assay. Results: The median age of the patients was 55 years (range, 16 to 86). A total of 55.4% of the patients had one or more coexisting medical conditions. The most common symptom was fever (95.2%). At admission, leukopenia (42.6%), thrombocytopenia (46.6%), and elevation of aspartate aminotransferase (42.7%) were observed. Pneumonia was detected in 68.3% of patients at admission and developed in 80.8% during the disease course. Antiviral agents were used for 74.7% of patients. Mechanical ventilation, extracorporeal membrane oxygenation, and convalescent serum were employed for 24.5%, 7.1%, and 3.8% of patients, respectively. Older age, presence of coexisting medical conditions including diabetes or chronic lung disease, presence of dyspnea, hypotension, and leukocytosis at admission, and the use of mechanical ventilation were revealed to be independent predictors of death. Conclusion: The clinical features of MERS-CoV infection in the Republic of Korea were similar to those of previous outbreaks in the Middle East. However, the overall mortality rate (20.4%) was lower than that in previous reports. Enhanced surveillance and active management of patients during the outbreak may have resulted in improved outcomes. FAU - Choi, Won Suk
ABSTRACT
Background: In 2015, an outbreak of Middle East Respiratory Syndrome coronavirus (MERS-CoV) infection occurred in South Korea involving 186 patients, 39 of whom were healthcare workers (HCWs) exposed to the infection. An effective post-exposure prophylaxis (PEP) strategy may limit the spread of infection;however, there is no consensus regarding PEP for MERS-CoV infection. In this study, we assessed (1) the efficacy of oral ribavirin and lopinavir/ritonavir as PEP for HCWs exposed to patients with severe MERS-CoV pre-isolation pneumonia, and (2) safety of the PEP regimen. Methods: We retrospectively enrolled 43 HCWs with high-risk exposure to MERS-CoV from 5 hospitals affected during this outbreak in South Korea. The rate of MERS-CoV infection was compared between 22 workers at 1 hospital who received PEP consisting of oral ribavirin and lopinavir/ritonavir after exposure to patients with severe MERS-CoV pre-isolation pneumonia and 21 workers at other hospitals who did not receive PEP. Results: Six workers (14%) developed MERS-CoV infection;all of these subjects belonged to the non-PEP group. The attack rate was lower in the PEP group compared with the non-PEP group (0% vs. 28.6%;Odds ratio = 0.405, 95% confidence interval = 0.274–0.599;P = 0.009). The most commonly reported side effects of PEP therapy were nausea and diarrhea, but there were no severe adverse effects associated with PEP therapy. Conclusion: PEP with a combination of oral ribavirin and lopinavir/ritonavir appears to be effective and generally safe for preventing MERS-CoV infection after high-risk exposure in healthcare workers. Disclosures: All authors: No reported disclosures. FAU - Park, So Yeon
ABSTRACT
Background/Objectives: Middle East Respiratory Syndrome(MERS) is caused by the MERS-Korona virus, a type of beta-corona virus, is a serious respiratory disease with numerous reported. The purpose of this study was to provide a comprehensive review of MERS in Korea in 2015 and use it as basic data for preventing future infectious diseases in Korea. Methods/Statistical analysis: This study was designed by the authority. The research material, after MERS-CoV's declaration of an end, the authorities searched the website of a reputable organization in Korea for a proven report on MERS-CoV. Findings: Of 111 male patients and 75 female patients with laboratory-confirmed MERS-CoV infections between May 20, and July 13, 2015, total 38(20.4% fatality rate) case died. The most common causes of infection occurred in hospital visits and hospital admissions. 82 (44.1%) patients;64(34.4%) were patients’ family, caregivers, or visitors;39(21.0%) were healthcare personnel, and one(0.5%) case was of unknown origin. It was associated with 16 medical institutions, most of them related to medical institutions. Improvements/Applications: Judging by this nature, isolation in the hospital of the initial and estimated superconductors is paramount and is an important criterion for prevention and isolation in the future 'Management and Countermeasures of Infectious Diseases'. © 2020, Hampstead Psychological Associates. All rights reserved.